Pyrrolizidine Alkaloids

Herb Forum Admin

Herb Forum Admin

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Let's talk about pyrrolizidine alkaloids (PAs). Pyrrolizidine alkaloids are found in a large number of plants, including many herbs. In most of the traditionally used herbs that have PAs, they haven't seemed to be an issue (but do note the usage is usually short term). However, given that pyrrolizidine alkaloids exhibit toxicity it would be good to know which herbs have them and to what concentration.
 
Occurrence and Risk Assessment of Pyrrolizidine Alkaloids in Spices and Culinary Herbs from Various Geographical Origins
www.ncbi.nlm.nih.gov

Occurrence and Risk Assessment of Pyrrolizidine Alkaloids in Spices and Culinary Herbs from Various Geographical Origins

Pyrrolizidine alkaloids (PA) and their N-oxides (PANO) are a group of toxic secondary plant metabolites occurring predominantly as contaminants in (herbal) teas, honeys and food supplements, as well as in spices and culinary herbs. Depending on the botanical ...
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
 
Current Knowledge and Perspectives of Pyrrolizidine Alkaloids in Pharmacological Applications: A Mini-Review
www.ncbi.nlm.nih.gov

Current Knowledge and Perspectives of Pyrrolizidine Alkaloids in Pharmacological Applications: A Mini-Review

Pyrrolizidine alkaloids (PAs) are a widespread group of secondary metabolites in plants. PAs are notorious for their acute hepatotoxicity, genotoxicity and neurological damage to humans and animals. In recent decades, the application of PAs for beneficial ...
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
 
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