Pyrrolizidine Alkaloids

Herb Forum Admin

Staff member
Let's talk about pyrrolizidine alkaloids (PAs). Pyrrolizidine alkaloids are found in a large number of plants, including many herbs. In most of the traditionally used herbs that have PAs, they haven't seemed to be an issue (but do note the usage is usually short term). However, given that pyrrolizidine alkaloids exhibit toxicity it would be good to know which herbs have them and to what concentration.
Occurrence and Risk Assessment of Pyrrolizidine Alkaloids in Spices and Culinary Herbs from Various Geographical Origins
Current Knowledge and Perspectives of Pyrrolizidine Alkaloids in Pharmacological Applications: A Mini-Review